Obagi NU-GEN™ Cellular Renewal Serum

Powered by NAD+ longevity science, Obagi NU-GEN™ Cellular Renewal Serum helps visibly rewind the skin’s age by up to 6 years¹ while supporting cellular renewal, resilience and radiance.

Next-generation longevity science for visible skin renewal.

Obagi NU-GEN™ Cellular Renewal Serum represents a breakthrough in professional skincare, moving beyond traditional anti-ageing to support the skin’s long-term biological performance. Powered by NAD+ technology and Obagi’s proprietary AGE CTRL™ Complex, this advanced serum helps replenish the cellular energy required for skin renewal, repair and visible vitality.

NAD+ is a vital coenzyme found in every skin cell, responsible for fuelling the processes that maintain healthy, resilient skin. However, NAD+ levels decline significantly with age (up to 50% by age 40), reducing the skin’s ability to repair, regenerate and defend itself against visible ageing. NU-GEN helps replenish this essential cellular energy source, by supporting the skin’s natural renewal pathways and driving visible improvements across the nine hallmarks of ageing.¹’²’³

Designed to work synergistically within any Obagi routine, NU-GEN functions as the first step after cleansing and toning, preparing the skin to receive and maximise the performance of subsequent treatments. As well as enhancing the efficacy of other formulas, it delivers visible benefits in its own right, helping to improve firmness, refine texture and restore radiance.

By supporting cellular communication, antioxidant defence and barrier recovery, NU-GEN targets the underlying drivers of skin ageing. The result is skin that appears healthier, more hydrated and more resilient today, while supporting stronger skin performance over time.

¹Results based on a 2025 12-week ageing clinical test. ²Results based on a 2025 12-week blemish-prone clinical test. ³Results based on a 2025 48-hour hydration clinical test. Individual results may vary. Data on file at Obagi Cosmeceuticals LLC.